Why was the chicken black and the other were white? Adoption!
Why do people with Down syndrome always look funny?
It’s their funny face.
You're so retarded, if there was a clone of you that was supposed to be smart, it would still be retarded.
Down syndrome and brownies.
Hey there, wanna buy some chromosomes?
"Rapeboat" has six fingers on each hand and one big eyebrow. Signs of inbreeding.
If BLESSEDBRIAN were any more inbred, he’d be a SANDWICH.
Hello, which do y'all think is more embarrassing to have, is it autism or Down syndrome?
Why did Sally not save the mountain climber?
Because it was her dad.
Doctor, Doctor, I discovered one of the base pairs in my genetic code is erroneously a stop codon?
Nonsense! That shouldn't be happening!
Which is more disabling, is it autism or Down syndrome?
Down syndrome sucks!
Your hairline receded just like your father did years ago.
What did the mongol say to his dog?
Down syndrome!
What's the difference between Cain Dashiell and Down syndrome?
Nothing.
What is the difference between me and a retard?
At least I have chromosomes.
Why aren't Down's syndrome jokes funny?
Because the format of them is ugly.
Why does my brother have no mom?