What's a person with Down syndrome's favorite detergent?
Downy.
Don't let an extra chromosome get you down.
Them: "You're ugly."
Me: "No, as ugly as your extra chromosome."
What do you call a person with Down syndrome in a bathtub?
Vegetable soup.
What's the difference between Cain Dashiell and Down syndrome?
Nothing.
What do you call it when a person with Down syndrome gets friendzoned?
Chromozoned.
Down Syndrome is already a joke.
Why did the Down syndrome person cross the road? Because there was a zebra crossing!
What do you call someone with Down Syndrome who smokes weed?
A baked potato.