Don't let an extra chromosome get you down.
What do you call a down syndrome person that was hit by a car?
Mash potato.
Down syndrome and brownies.
Touch Down.
Fuck off!
Them: "You're ugly."
Me: "No, as ugly as your extra chromosome."
I named my dog Syndrome, so when he sits on my couch I say, “Get down, Syndrome!”
My syndrome may be down, but my hopes are always up.
What do you call a person with Down syndrome in a bathtub?
Vegetable soup.
What's the difference between Cain Dashiell and Down syndrome?
Nothing.
What do you call it when a person with Down syndrome gets friendzoned?
Chromozoned.
People with Down syndrome have a specific skill only they have; they can give a blow job and talk to you while sounding exactly the same.
Down Syndrome is already a joke.
Why did the Down syndrome person cross the road? Because there was a zebra crossing!
My life.
If a midget with down syndrome shows up late for work, is it okay to say she's a little tardy?
What's simultaneously up and down?
A retard on a plane.
How do you tell if a loaf of bread has Down Syndrome?
It has an extra crumb-osome.
What do you call someone with Down Syndrome who smokes weed?
A baked potato.