I would make a disabled joke.
But they never work.
I know a girl in a wheelchair. I realize now why she couldn’t do sports because the coaches wanted 100% from her, but she was only able to give 50%.
I walked into the school for disabled kids and asked them if they knew how to play "Heads, Shoulders, Knees, and Toes." Turns out they only knew how to play "Heads, Shoulders, Wheels, and Frame."
Why did the Down syndrome person cross the road? Because there was a zebra crossing!