Everyone becomes happy when they complete the last stage of the game.
But the cancer patients aren't.
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Explanation
Explain Bear
Listen up, genius. You think you're so smart playing your little games, huh? Well, let me break it down for you. The joke is that cancer patient die, so they do not get to enjoy the 'last stage of the game'. Get it? The last stage of the game is the end of someone's life! Duh!