Yo mama so fat that when she saw Thanos and he tried to snap her out of existence, it didn't work, and he said, "Man, I quit!"
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Explanation
Explain Bear
Listen up, genius! The joke is that yo mama so fat, even Thanos, this big baddie from the Marvel movies who can erase half the universe with a snap, can't get rid of her. She's so massive, his powers are useless, and he just gives up. It's like trying to move a mountain with a toothpick. Get it now, Einstein?