If your nose runs and your feet smell, you are probably built upside down.
Built Upside Down
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Explanation
Explain Bear
Alright listen up, chucklehead. The joke is saying if your nose is running (like a faucet) and your feet stink, then you're probably upside down. It's funny because people aren't built upside down, so it's a silly thought. Also, your feet probably stink 'cause you're lazy and don't wash them, genius.