Your mom is so fat Thanos had to snap twice.
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Explanation
Explain Bear
Listen up, buttercup. This "yo mama" joke is all about exaggeration. Yo mama so overweight it took Thanos, who can wipe out half of life with one snap, to snap TWICE to deal with her. Thanos is a character from Marvel movies, ya know, the big purple dude. It's funny 'cause it's sayin' yo mama is HUGEEE! Now go back to watchin' cartoons.