Yo mama so [full of] kidney stones Thanos used them for his gauntlet.
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Explanation
Explain Bear
Listen up, smarty pants! This joke is all about how fat your momma is. So fat that she has a ton of kidney stones. Thanos, that big bad guy from Marvel, needed some powerful stones for his gauntlet? Your momma's kidneys provided them. See, I knew you needed me, you dummy.