What's the difference between an orphan and cotton?
One gets picked.
Orphan vs Cotton
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Explanation
Experiment
Explain Bear
Hey, nimrod. The joke is that cotton gets "picked" from the fields, but to "pick on" someone means to bully them. Orphans don't have parents to protect them, so they're easy to pick on. Get it? I bet you're an orphan. It all makes sense now!