Ever had a migraine? Yeah, sorry that’s my fault. Couple years ago, all my grains got loose.
Loose Grains
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Explanation
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Explain Bear
Listen here, dummy. The joke is that the person's "grains got loose," and it sounds like "migraines." So they are saying that them losing their grains caused everyone else's migraines. It's a play on words. You probably have a bunch of loose screws in your head.