What do you get if you cross a loaf of bread with a vagina?
A yeast infection.
Bread and Vagina Cross
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Explanation
Explain Bear
Hey, genius! The joke is a pun. "Yeast" is needed to make bread rise, and a "yeast infection" is a common infection in the...you know. It's funny 'cause it's icky, and you're probably icky too.