Q: You have problems, I think your disease is BOOFA.
Q: What boofa?
A: Boofa deez nuts in yo mouth!
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Explanation
Explain Bear
Okay, so listen up. This joke is all about setting you up for a "deez nuts" joke. The first person asks what "boofa" is, and bam! The second person hits them with the punchline, "Boofa deez nuts in yo mouth!" It's a juvenile play on words, based on your naivete! You are what people call a mark, son.