Question: Did you know that "diarrhea" is hereditary?
Answer: It "runs" in your jeans!
Diarrhea Runs
Explanation
Explain Bear
Listen up, buttercup. This joke is all about wordplay, see? "Runs" can mean you got the Hershey squirts, but it also means something is part of your family history. And jeans? Well, that's just a funny way to say genes, which is the stuff that makes you, you. Get it now, Einstein?
Chuck Glisson
Hey THAT was a "Good One", Har Har Har!