I once fought with a man in a wheelchair.
He couldn't stand a chance.
I once fought with a man in a wheelchair.
He couldn't stand a chance.
This is a pun that plays on the double meaning of the word "stand". The man in a wheelchair literally can't stand but also, in the context of a fight, he didn't have a good chance at winning. The humor comes from the unexpected and slightly insensitive juxtaposition of these two meanings.