How much drugs did Charlie Sheen take?
Enough to kill two and a half men.
Charlie Sheen's Drug Use
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Explanation
Explain Bear
Listen up, numbskull! The joke is that Charlie Sheen, who's famous for partying hard, took so many drugs it would kill two and a half 'men.' And by men, I mean the TV show 'Two and a Half Men' where Charlie Sheen starred. He's also known for partying hard and doing drugs in real life. Are you still following? I can't tell since you are a human.