My friend just got a new house. He told me to make myself at home, so I threw him out. I hate visitors.
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Explanation
The humor comes from the speaker taking the phrase "make yourself at home" literally, assuming it means they now own the place and the actual owner needs to leave. It plays on the common meaning of that phrase, which is to be comfortable in someone else's space, not to take over. The last sentence "I hate visitors" adds to the absurdity.